TARE Y-90 therapy is a radiation-based treatment for liver cancer that uses a radioactive substance called Yttrium-90 to directly target tumors. During the procedure, microscopic particles containing Y-90 are delivered into the blood vessels that supply the tumor, allowing radiation to act precisely at the cancer site. This approach enables effective destruction of cancer cells while minimizing damage to surrounding healthy liver tissue. In addition, Y-90 therapy helps shrink tumors, which can prolong survival, reduce symptoms, and improve overall quality of life.
At Mandaya Royal Hospital Puri, TARE Y-90 therapy is available and performed by an interventional radiology specialist, dr. Sugianto Santoso, Sp.Rad (K)RI.
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How does TARE Y-90 therapy work to treat liver cancer without surgery?
In general, the process of TARE Y-90 therapy includes the following steps:
- Before the main procedure, a mapping angiogram is performed to visualize the blood vessels supplying the tumor. This helps determine the most effective pathway for delivering Y-90 particles.
- Microscopic particles containing Y-90 are then injected into the blood vessels feeding the tumor in the liver.
- These particles travel through the bloodstream directly to the tumor.
- Once they reach the tumor, the Y-90 emits high-dose radiation to destroy cancer cells.
- The radiation is highly targeted, minimizing damage to surrounding healthy liver tissue.
- By controlling tumor growth, this therapy can help patients live longer, experience fewer symptoms, and achieve a better quality of life.
Who is eligible for TARE Y-90 therapy?
TARE Y-90 therapy is generally recommended for patients with liver cancer who are not suitable candidates for surgery. It can also be considered in certain conditions to control tumor growth while preserving liver function and potentially opening the door to future treatments.
- Patients with primary liver cancer
- Patients with cancer that has spread to the liver (metastasis)
- Patients who cannot undergo surgery, for example due to tumors located near major blood vessels
- Patients who need to slow tumor progression while maintaining liver function
- Patients being prepared for further treatments such as surgery or liver transplantation after tumor size is reduced
What happens after TARE Y-90 therapy?
After undergoing Y-90 therapy, patients are typically monitored in a recovery room for about 4–5 hours. In some cases, an overnight hospital stay may be recommended for further observation, but most patients can return home the same day. Once the patient is stable, vital signs are normal, and they can move safely, discharge is usually allowed.
The next steps depend on each patient’s treatment plan. Some patients may only need a single Y-90 session, while others may require multiple treatments. Additional therapies such as chemotherapy or surgery may also be needed, depending on the condition and progression of the disease.
How effective is TARE Y-90 therapy?
TARE Y-90 therapy has been shown to extend the life expectancy of patients with inoperable liver cancer from just a few months to around 2–3 years. It also helps relieve symptoms, allowing patients to experience a better quality of life.
Today, Y-90 therapy is increasingly used as an initial step before more definitive treatments, such as surgery.
TARE Y-90 Therapy at Mandaya Royal Hospital Puri with dr. Sugi, Sp.Rad (K)RI

dr. Sugianto Santoso, Sp.Rad (K)RI is a radiology specialist with a subspecialty in interventional radiology, experienced in performing various minimally invasive procedures using advanced imaging technology. He completed his medical degree at Maranatha Christian University in Bandung and pursued his radiology specialization at the University of Indonesia.
In his practice, dr. Sugianto Santoso treats a wide range of conditions without the need for open surgery, including liver cancer and other complex diseases. His expertise includes procedures such as Radiofrequency Ablation (RFA) for thyroid nodules, Microwave Ablation (MWA) for tumors and liver cancer, and Transarterial Chemoembolization (TACE) as a liver cancer treatment.
With the support of advanced medical technology and a minimally invasive approach, dr. Sugi provides safer, more precise, and effective treatment options, including TARE Y-90 therapy and other interventional procedures at Mandaya Royal Hospital Puri.
To make your visit to Mandaya Royal Hospital Puri more convenient, you can use the WhatsApp Chat feature, Book Appointment service, or the Care Dokter application available on Google Play and the App Store to check queue numbers and access more information.
The information on this page is intended for educational and general purposes only and does not represent the full range of medical services provided by each doctor. For appropriate treatment based on your condition, it is recommended to consult directly with the respective doctor.
If you have any questions or need further information, please contact our call center at 0811-1900-2000.

