HIPEC (Hyperthermic Intraperitoneal Chemotherapy) is an advanced cancer treatment innovation designed to manage advanced colorectal and ovarian cancer that has spread to the abdominal cavity (peritoneum). This cutting-edge technology, previously available only in leading hospitals in Singapore and Malaysia, can now be accessed in Indonesia through Mandaya Royal Puri Hospital.
Unlike conventional chemotherapy, which is administered over multiple cycles, HIPEC is performed in a single session. One of its main advantages is the ability to directly destroy microscopic cancer cells within the abdominal cavity while minimizing side effects.
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Understanding HIPEC Chemotherapy at Mandaya Royal Puri Hospital
HIPEC is one of the most advanced cancer treatment methods designed to target tumors within the peritoneal cavity, the area that protects vital organs such as the liver, stomach, and intestines.
This procedure is performed after the primary tumor has been surgically removed, followed by the administration of heated chemotherapy drugs (40–50°C) circulated directly into the abdominal cavity to eliminate any remaining microscopic cancer cells. The combination of heat and chemotherapy produces a synergistic effect that enhances treatment effectiveness.
The HIPEC procedure consists of two main stages performed in a single surgical session:
- Cytoreductive Surgery (CRS) – In this first stage, surgeons remove as much visible tumor tissue as possible from the abdominal cavity. Under general anesthesia, the surgical team carefully examines and removes the affected tissues to reduce the tumor burden and prepare the area for heated chemotherapy.
- Hyperthermic Intraperitoneal Chemotherapy (HIPEC) – After all visible tumors are removed, heated chemotherapy fluid is circulated throughout the abdominal cavity using a specialized perfusion machine via catheters. The fluid is maintained for 1–2 hours to ensure even exposure before being drained and replaced with a sterile solution, and the incision is then carefully closed.
Advantages of HIPEC Chemotherapy for Colorectal and Ovarian Cancer Spread to the Abdominal Cavity
HIPEC offers several benefits, making it one of the most effective treatment options for peritoneal cancer today:
- Targets areas that systemic chemotherapy cannot easily reach, as the heated drug is delivered directly into the abdominal cavity.
- Provides higher accuracy in targeting and destroying microscopic cancer cells that are invisible during surgery.
- Uses high temperatures (40–50°C) to enhance the potency of chemotherapy drugs without increasing side effects.
- Performed in a single surgical session, eliminating the need for multiple chemotherapy cycles.
- Causes fewer side effects since the drugs act locally and are minimally absorbed into the bloodstream.
- Improves survival outcomes and quality of life for patients with advanced-stage cancers that have spread to the peritoneum.
Specialist Team Performing HIPEC Chemotherapy at Mandaya Royal Puri Hospital
The HIPEC procedure at Mandaya Royal Puri Hospital is carried out by a team of digestive surgery and gynecologic oncology specialists with extensive experience and specialized expertise in treating peritoneal cancer and performing complex abdominal and pelvic surgeries.
1. dr. Ocsyavina, Sp.B, Subsp.BD (K)
dr. Ocsyavina is a digestive surgery specialist with extensive experience in managing various gastrointestinal conditions, including colorectal cancer, peritoneal tumors, and complex intestinal diseases. She is known for her precision, clear communication, and dedication to patient safety and comfort. Her surgical approach is characterized by a deep understanding of gastrointestinal anatomy and physiology, ensuring accuracy and optimal results.
Practice Schedule:
- Monday – Friday: 16.00 – 18.00 WIB
- Saturday: 10.00 – 12.00 WIB
2. dr. Emerson Budiarman Masli, Sp.B, Subsp.BD (K)
dr. Emerson Budiarman Masli is a digestive surgery specialist with strong expertise in treating various gastrointestinal diseases such as gallstones, hernias, appendicitis, liver cancer, and colorectal cancer. He is known for his meticulous surgical techniques that minimize postoperative complications. In the HIPEC procedure, dr. Emerson plays a vital role in the cytoreductive surgery phase, ensuring all visible tumor tissues are optimally removed.
Practice Schedule:
- Monday & Wednesday: 10.00 – 13.00 WIB
3. Prof. Dr. dr. Toar Jean Maurice Lalisang, Sp.B, Subsp.BD (K)
Prof. Toar Jean Maurice Lalisang is one of Indonesia’s most prominent experts in digestive surgery. As a senior surgeon and educator, he has made significant contributions to advancing surgical techniques and education in Indonesia, including complex procedures such as HIPEC. His vast experience includes liver transplantation, pancreatic surgery, and colorectal tumor resections.
Practice Schedule:
- Tuesday & Thursday: 15.30 – 17.30 WIB
- Saturday: 11.00 – 13.00 WIB
4. dr. Ong Tjandra, M.Kes, Sp.OG (K), Subsp. Onk
dr. Ong Tjandra is a consultant obstetrician-gynecologist specializing in oncology, with extensive experience treating ovarian, cervical, and uterine cancers, as well as various benign reproductive tumors. He emphasizes a holistic approach, focusing not only on cancer treatment but also on improving patients’ post-therapy quality of life. Within the HIPEC team at Mandaya Royal Puri Hospital, dr. Ong conducts comprehensive evaluations for advanced ovarian cancer patients to determine appropriate indications for the procedure.
Practice Schedule:
- Monday: 10.00 – 17.00 WIB
- Thursday: 16.00 – 20.00 WIB
5. Dr. dr. Unedo Hence Markus Sihombing, Sp.OG, Subsp. Onk
Dr. Unedo Hence Markus Sihombing is a gynecologic oncology consultant experienced in managing ovarian, endometrial, and vulvar cancers, as well as benign conditions such as myomas and ovarian cysts. He is known for his compassionate, patient-centered approach and dedication to achieving optimal treatment outcomes. In the HIPEC procedure, Dr. Unedo plays a key role in performing advanced ovarian cancer surgeries, combining surgical expertise with intraperitoneal chemotherapy for maximum therapeutic effectiveness.
Practice Schedule:
- Tuesday & Thursday: 16.00 – 20.00 WIB
- Saturday: 13.00 – 16.00 WIB
If you would like to learn more about the HIPEC chemotherapy procedure for advanced colorectal or ovarian cancer, feel free to visit Mandaya Royal Puri Hospital.
To make your visit easier, you can use the Chat via WhatsApp, Book Appointment, or the Care Dokter app, available on Google Play and the App Store, to schedule appointments, check queue numbers, and access complete service information conveniently.
