Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is an advanced cancer treatment method designed to target tumors located in the abdominal cavity (peritoneum) — the area that houses vital organs such as the liver, stomach, and intestines. In this procedure, surgeons first remove all visible cancerous tumors, then circulate heated chemotherapy drugs inside the abdominal cavity to eliminate any remaining microscopic cancer cells after surgery.
HIPEC is primarily used to treat cancers that have spread (metastasized) from other organs to the peritoneum, including advanced-stage colon cancer.
RS Mandaya Royal Puri is the first and only hospital in Indonesia to provide HIPEC chemotherapy services. So, what are the advantages of HIPEC chemotherapy for colon cancer that has spread to the abdominal cavity?
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Advantages of HIPEC Chemotherapy for Colon Cancer That Has Spread to the Abdominal Cavity
Here are several benefits of HIPEC chemotherapy for patients with metastatic colon cancer:
1. Targets areas unreachable by systemic chemotherapy
Traditional chemotherapy drugs circulate through the bloodstream and often cannot penetrate the peritoneal lining (the membrane that covers the abdominal cavity).
HIPEC delivers heated chemotherapy drugs directly into the peritoneal cavity, allowing it to reach cancer cells that conventional systemic chemotherapy cannot access.
2. Destroys cancer cells directly and more effectively
Because the chemotherapy drugs are applied directly to the tumor site, HIPEC can destroy cancer cells with higher precision. This process eliminates residual microscopic cancer cells that may remain after surgical tumor removal.
3. Uses high-dose heated drugs for stronger cancer-killing effects
In HIPEC, chemotherapy drugs are heated to around 40–50°C before being circulated throughout the abdominal cavity. The heat enhances the drug’s potency, improving absorption into cancerous tissue and increasing its overall effectiveness in destroying cancer cells compared to standard chemotherapy.
4. Completed in a single treatment session
Unlike systemic chemotherapy that requires multiple sessions or “cycles,” HIPEC is performed once during surgery. After tumor removal, the heated chemotherapy solution is circulated for 30–90 minutes, making the entire process more efficient and reducing the patient’s overall treatment time.
5. Causes fewer side effects than conventional chemotherapy
Since HIPEC drugs remain localized within the abdominal cavity and are minimally absorbed into the bloodstream, patients experience fewer systemic side effects such as hair loss, nausea, or organ toxicity.
This localized approach allows patients to recover faster and more comfortably after the procedure.
6. A more advanced treatment option for late-stage cancer
HIPEC represents a breakthrough for patients with advanced colon cancer that has spread to the abdominal cavity, offering a higher survival rate and lower recurrence risk.
In Indonesia, this innovative procedure is now available exclusively at RS Mandaya Royal Puri, the country’s first hospital to introduce HIPEC technology.
How is the HIPEC Chemotherapy Procedure Performed for Colon Cancer?
The HIPEC procedure consists of two interconnected stages: Cytoreductive Surgery (CRS) and Heated Intraperitoneal Chemotherapy (HIPEC) itself.
1. Cytoreductive Surgery (CRS)
In the first stage, the surgeon removes as much visible cancer tissue as possible from the abdominal cavity.
While the patient is under general anesthesia, the surgeon makes an incision in the abdomen to examine and carefully remove infected tissue or organs. The goal is to reduce the tumor burden as much as possible so that the subsequent heated chemotherapy can effectively target remaining microscopic cancer cells.
2. HIPEC Stage
After all visible cancer tissues are removed, the surgeon proceeds with the HIPEC stage. A special catheter is inserted into the abdominal cavity and connected to a perfusion machine that heats the chemotherapy drugs to around 40–50°C. The heated solution is then circulated evenly throughout the cavity for 1–2 hours.
This process aims to destroy microscopic cancer cells that might still remain after surgery. Once the circulation process is complete, the chemotherapy fluid is drained, and the abdominal cavity is rinsed with sterile saline before the incision is closed carefully.
Doctors Performing HIPEC Procedures at RS Mandaya Royal Puri
Below are the doctors at RS Mandaya Royal Puri who perform HIPEC procedures for advanced colon cancer:
1. dr. Ocsyavina, Sp.B. Subsp.BD (K)
Dr. Ocsyavina is a Digestive Surgery Specialist at RS Mandaya Royal Puri with extensive expertise in treating various gastrointestinal diseases, including stomach disorders, intestinal conditions, gallbladder diseases, colorectal cancer, and abdominal tumors.
With her strong academic background and broad clinical experience, Dr. Ocsyavina is known for her thorough, communicative, and patient-centered approach, always prioritizing safety and comfort in every surgical procedure.
Practice Schedule:
- Monday: 16.00 – 18.00 WIB
- Tuesday: 16.00 – 18.00 WIB
- Wednesday: 16.00 – 18.00 WIB
- Thursday: 16.00 – 18.00 WIB
- Friday: 16.00 – 18.00 WIB
- Saturday: 10.00 – 12.00 WIB
2. dr. Emerson Budiarman Masli, Sp.B. Subsp.BD (K)
Dr. Emerson Budiarman Masli is a Digestive Surgery Specialist at RS Mandaya Royal Puri with broad experience in handling digestive system disorders.
He is skilled in performing surgeries for gallstones, appendicitis, hernias, liver cancer, and colon cancer using a precision-based, patient-centered approach to ensure the best possible outcomes.
Practice Schedule:
- Monday: 10.00 – 13.00 WIB
- Wednesday: 10.00 – 13.00 WIB
3. Prof. Dr. dr. Toar Jean Maurice Lalisang, Sp.B. Subsp.BD (K)
Prof. Dr. Toar Jean Maurice Lalisang is one of Indonesia’s most respected senior Digestive Surgery Specialists. He has extensive experience and a strong reputation in managing complex gastrointestinal surgical cases and liver transplant procedures. As a leading expert in his field, Prof. Toar has made significant contributions to the advancement of digestive surgery in Indonesia through clinical practice, research, and medical education.
He is widely recognized as a highly dedicated physician and mentor to many young surgeons across the country.
Practice Schedule:
- Tuesday: 15.30 – 17.30 WIB
- Thursday: 15.30 – 17.30 WIB
- Saturday: 11.00 – 13.00 WIB
If you would like to learn more about the HIPEC chemotherapy procedure for treating colon cancer that has spread to the abdominal cavity, visit RS Mandaya Royal Puri.
To make your visit easier, you can use the Chat via WhatsApp, Book Appointment, or the Care Dokter App, available on Google Play and the App Store, to check queue numbers, schedule appointments, and access complete hospital information conveniently.
