Late-stage colon cancer is a condition in which cancer cells have grown more aggressively and spread to other organs or tissues in the body, including the abdominal cavity. At this advanced stage, symptoms typically become more severe, such as significant weight loss, abdominal pain, digestive disturbances, and a decline in overall quality of life. Managing cancer at this stage requires a more comprehensive and targeted treatment approach to help control its spread and improve the patient’s chances of survival.
RS Mandaya Royal Puri offers the advanced CRS-HIPEC (Cytoreductive Surgery – Hyperthermic Intraperitoneal Chemotherapy) procedure for patients with late-stage colon cancer that has metastasized to the abdominal cavity. Through a combination of tumor-reducing surgery and heated chemotherapy delivered directly into the abdominal cavity, CRS-HIPEC helps destroy cancer cells more effectively and improves the likelihood of better treatment outcomes.
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CRS-HIPEC Treatment for Late-Stage Colon Cancer at Mandaya
The CRS-HIPEC treatment consists of two main phases: cytoreductive surgery (CRS) and HIPEC. Below are the detailed steps:
1. Cytoreductive Surgery (CRS)
In the initial phase, the surgeon removes as much visible cancer tissue or tumor mass as possible from the abdominal cavity. This surgery is performed under general anesthesia, during which the doctor makes an incision in the abdominal area to assess the organs and remove detected tumors. This step aims to significantly reduce the cancer burden before administering heated chemotherapy.
2. HIPEC Procedure
Once all visible cancerous tissue has been removed, the procedure continues with HIPEC therapy. During this phase, a special catheter is inserted into the abdominal cavity and connected to a perfusion machine that heats chemotherapy drugs to approximately 40–50°C. The heated chemotherapy is then circulated evenly throughout the abdominal cavity for about 1–2 hours.
The goal is to destroy microscopic cancer cells that may remain after surgery. After the process is completed, the chemotherapy fluid is drained, the abdominal cavity is rinsed with sterile saline, and the incision is closed.
Advantages of CRS-HIPEC for Late-Stage Colon Cancer Spread to the Abdominal Cavity
Below are the key benefits of HIPEC for treating colon cancer that has metastasized to the abdominal cavity:
1. Reaches Areas Unaffected by Systemic Chemotherapy
Systemic chemotherapy delivered through the bloodstream often cannot penetrate the peritoneal lining, leaving certain areas in the abdominal cavity untreated. HIPEC overcomes this limitation by delivering chemotherapy drugs directly into the abdominal cavity, allowing it to target cancer cells unreachable by conventional chemotherapy.
2. More Effective in Killing Cancer Cells Directly
With HIPEC, chemotherapy is administered at the precise site of cancer spread. This localized approach enables more accurate destruction of cancer cells, including microscopic cells that may remain after surgery.
3. Higher Doses and Stronger Effects Due to Heat
Chemotherapy drugs used in HIPEC are heated to around 40–50°C before circulation. The heat enhances the drug’s ability to penetrate tumor tissues and increases its cancer-killing potency, making it more effective than standard chemotherapy.
4. Completed in a Single Operative Session
Unlike systemic chemotherapy, which requires multiple cycles, HIPEC is performed once during the same surgical session. After the main tumor is removed, the heated chemotherapy is administered for 30–90 minutes, making the treatment more efficient.
5. Fewer Side Effects
Because the chemotherapy used in HIPEC is contained within the abdominal cavity and only a small amount enters the bloodstream, the risk of systemic side effects—such as severe nausea, hair loss, or organ damage—is significantly reduced. This allows patients to recover more comfortably and quickly.
6. A More Advanced Option for Late-Stage Cancer
HIPEC is considered a modern treatment breakthrough for late-stage colon cancer that has spread to the abdominal cavity. This method reduces the risk of recurrence and enhances the overall success of cancer treatment.
Colon Cancer Specialists at RS Mandaya Royal Puri
1. dr. Ocsyavina, Sp.B. Subsp.BD (K)
dr. Ocsyavina, Sp.B. Subsp.BD (K), is a digestive surgery specialist at RS Mandaya Royal Puri. She has extensive expertise in treating various digestive system diseases, including stomach, intestinal, and gallbladder disorders, as well as colorectal cancer and abdominal tumors. With strong clinical experience and advanced training, she is known for her thoroughness, clear communication, and commitment to patient safety and comfort.
Clinic hours:
- Monday: 16.00–18.00 WIB
- Tuesday: 16.00–18.00 WIB
- Wednesday: 16.00–18.00 WIB
- Thursday: 16.00–18.00 WIB
- Friday: 16.00–18.00 WIB
- Saturday: 10.00–12.00 WIB
2. dr. Emerson Budiarman Masli, Sp.B. Subsp.BD (K)
dr. Emerson Budiarman Masli, Sp.B. Subsp.BD (K), is an experienced digestive surgeon who also practices at RS Mandaya Royal Puri. He specializes in treating digestive issues such as gallstones, appendicitis, and hernias, as well as performing surgical procedures for liver and colon cancer. His precise surgical techniques and strong focus on patient safety make him one of the trusted specialists in the field
Clinic hours:
- Monday: 10.00–13.00 WIB
- Wednesday: 10.00–13.00 WIB
3. Prof. Dr. dr. Toar Jean Maurice Lalisang, Sp.B. Subsp.BD (K)
Prof. Dr. dr. Toar Jean Maurice Lalisang, Sp.B. Subsp.BD (K), is a highly respected senior digestive surgery specialist. He has extensive experience managing complex digestive cases and is widely recognized as one of Indonesia’s leading experts in liver transplantation.
In addition to his clinical practice, Prof. Toar plays an important role in advancing digestive surgery in Indonesia through research, academic contributions, and mentoring young surgeons. He is known for his dedication, expertise, and profound commitment to medical education.
Clinic hours:
- Tuesday: 15.30–17.30 WIB
- Thursday: 15.30–17.30 WIB
- Saturday: 11.00–13.00 WIB
To simplify your visit to Mandaya Royal Hospital Puri, you can use the WhatsApp Chat feature, Book Appointment service, or the Care Dokter app—available on Google Play and the App Store—to check queue numbers and access complete hospital information.
