Pancreatic Cancer Symptoms to Watch Out For, Including Commonly Overlooked Early Signs

Gejala Kanker Pankreas yang Perlu Diwaspadai, Termasuk Tanda Awal yang Sering Terabaikan

Pancreatic cancer is a type of cancer that develops in the pancreas, an organ that plays an important role in digestion. This cancer is considered aggressive because it can develop without causing noticeable symptoms in its early stages. As a result, many patients only discover they have pancreatic cancer when the disease has reached an advanced stage or spread to other organs.

Although early signs can be difficult to recognize, certain changes in the body may indicate pancreatic cancer. Some of these symptoms may resemble common digestive problems and are therefore often overlooked. By recognizing the symptoms early, you can be more alert to potential warning signs and consult a doctor promptly if you experience unusual symptoms.

What Are the Pancreatic Cancer Symptoms to Watch Out For?

Pancreatic cancer often does not cause symptoms in its early stages. Symptoms usually begin to appear when the tumor has grown or spread to other parts of the body. These symptoms can also resemble common digestive problems, making it important to recognize changes in your body that may require medical attention.

Some symptoms of pancreatic cancer include:

  • Abdominal pain that spreads to the back: Pain may occur in the upper abdomen and radiate to the sides or back.
  • Unexplained weight loss: Losing weight even though you are not following a diet.
  • Yellowing of the skin and eyes (jaundice): This occurs due to a buildup of bilirubin in the body.
  • Fatigue and weakness: Feeling unusually tired or lacking energy despite getting enough rest.
  • Loss of appetite: Having less desire to eat or feeling full more quickly than usual.
  • Dark-colored urine: Urine becomes darker than usual.
  • Nausea: This may be accompanied by abdominal discomfort.
  • Changes in stool color and shape: Stool may appear pale or float.
  • Newly diagnosed or poorly controlled diabetes: Pancreatic cancer can affect insulin production and function.
  • Pain or swelling in the arms or legs: This may be associated with the formation of blood clots.
  • Itchy skin: This can occur due to a buildup of bilirubin, particularly when the bile duct is blocked.

Symptoms of Pancreatic Cancer That Has Spread to Other Organs

Pancreatic cancer can spread to other organs, particularly the liver, lungs, and the tissue lining the abdominal cavity. In less common cases, cancer cells may also spread to the bones.

When cancer spreads to the abdominal cavity, fluid may accumulate inside the abdomen. This condition is called ascites and can cause the abdomen to become enlarged, feel full, or become uncomfortable. The symptoms may vary depending on which organs are affected.

Pancreatic Cancer Treatment at Mandaya Royal Hospital Puri

Pancreatic cancer treatment needs to be tailored to the stage of the disease, the tumor’s location and size, the patient’s overall health, and whether the cancer can be surgically removed. Doctors may recommend one treatment method or a combination of therapies to control cancer cell growth and improve the patient’s quality of life.

Some treatment options for pancreatic cancer include:

  • Surgery: Surgery aims to remove the tumor and cancer-affected tissue. It is generally considered when the cancer is still localized and doctors believe that all cancerous tissue can be removed.
  • Chemotherapy: This treatment uses medications to kill cancer cells or slow their growth. Chemotherapy may be given before surgery to shrink the tumor, after surgery to destroy remaining cancer cells, or as the primary treatment for advanced cancer.
  • Radiotherapy: This treatment uses high-energy radiation to destroy cancer cells. It may be combined with chemotherapy or given before or after surgery, depending on the patient’s condition.
  • Targeted therapy: This treatment uses medications that target specific proteins or mechanisms that help cancer cells grow and spread. The choice of medication depends on the characteristics of the cancer and examination results, including biomarker or genetic testing when necessary.

At Mandaya Royal Hospital Puri, patients can consult with a team of specialists involved in pancreatic cancer care to receive an evaluation and treatment plan tailored to their condition. Through a multidisciplinary approach, treatment options can be considered based on examination results, cancer stage, and the patient’s overall health.

HIFU Therapy for Pancreatic Cancer at Mandaya Royal Hospital Puri

HIFU (High-Intensity Focused Ultrasound) therapy may help reduce pain experienced by patients with pancreatic cancer by shrinking the tumor and destroying sensory nerves around it that transmit pain signals.

Some potential advantages of HIFU therapy include:

  • Minimally invasive: The procedure does not require surgical incisions, which may lower the risk of infection and bleeding, reduce pain, and allow for a potentially shorter recovery period.
  • Image-guided treatment: Imaging helps doctors direct ultrasound energy toward the tumor, minimizing damage to surrounding healthy tissue.
  • No ionizing radiation: HIFU does not use ionizing radiation, which may reduce the risk of certain side effects and allow treatment to be repeated when medically indicated.
  • Potential to trigger an antitumor immune response: Destroying cancer cells may make tumor antigens more recognizable to the immune system.
  • Potential to improve immunotherapy effectiveness: HIFU may help increase the response of cancer cells to certain immunotherapy medications.

The choice of pancreatic cancer treatment, including the possibility of using HIFU, needs to be based on the cancer stage, tumor size and location, the patient’s overall health, and medical examination results. Not all patients meet the criteria for this therapy. Consultation with a specialist is necessary to determine the most appropriate treatment option.

Facilities for Out-of-Town and International Patients at Mandaya Royal Hospital Puri

Mandaya Royal Hospital Puri provides various support facilities to ensure greater comfort for patients traveling from other cities or countries:

  • VIP transport: A pickup service from Soekarno-Hatta International Airport, train stations, or seaports to the hospital in a comfortable vehicle, accompanied by a Patient Experience Officer (PEO).
  • Medical ambulance pickup: A dedicated pickup service for patients with specific medical needs from their arrival point (airport, train station, or seaport), equipped with medical equipment and accompanied by professional healthcare personnel.
  • Accommodation (Sleep Hub and apartments): Comfortable accommodation for patients’ families, located on the 8th floor of the Mandaya Royal Puri building, with nearby apartment options also available.
  • International Patient Relation: Dedicated assistance for international patients, including medical coordination, interpretation, and administrative support. For information and assistance, contact International Patient Relation at 021 5092 8888 or email [email protected].

To make your visit to Mandaya Royal Hospital Puri easier, use the WhatsApp Chat feature, Book Appointment service, or the Care Dokter application, available for download on Google Play and the App Store. These services allow you to manage your visit, check queue numbers, and access other important information.

The information provided on this page is intended for educational purposes and general guidance. It does not represent the full range of medical services that each doctor may provide. To ensure that you receive care appropriate to your health condition, we recommend consulting the relevant doctor directly.

If you have any questions, suggestions, or need further information, please contact our call center at 0811-1900-2000.

References

  1. Cleveland Clinic. Pancreatic Cancer: Symptoms, Causes & Treatment. (https://my.clevelandclinic.org/health/diseases/15806-pancreatic-cancer). Accessed on November 3, 2026.
  2. Mayo Clinic. Pancreatic Cancer: Symptoms and Causes. (https://www.mayoclinic.org/diseases-conditions/pancreatic-cancer/symptoms-causes/syc-20355421). Accessed on November 3, 2026.
  3. Focused Ultrasound Foundation. Pancreatic Cancer. (https://www.fusfoundation.org/diseases-and-conditions/pancreatic-cancer/). Accessed on November 3, 2026.
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