A kidney transplant is a medical procedure to replace a damaged kidney with a healthy one from a donor, either from a family member or a non-relative. This treatment is usually recommended for patients suffering from chronic kidney failure or end-stage renal disease (ESRD) when other therapies—such as medications or dialysis—are no longer effective. Through kidney transplantation, patients can achieve a better quality of life, reduced dependence on dialysis machines, and longer life expectancy.
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When Is a Kidney Transplant Necessary?
Here are several medical indications where a kidney transplant may be needed:
1. End-Stage Chronic Kidney Disease (CKD)
Chronic kidney disease is the most common cause of kidney transplantation. This condition occurs when kidney function gradually and permanently declines, making it unable to filter toxins from the blood.
In the final stage (stage 5), kidney function drops to less than 15% of normal capacity. At this point, patients cannot survive without replacement therapy such as dialysis or kidney transplantation.
Transplantation offers the best long-term solution because it can fully and permanently restore kidney function.
2. Kidney Failure Due to Diabetes (Diabetic Nephropathy)
Long-term diabetes can damage the small blood vessels in the kidneys due to uncontrolled blood sugar levels, a condition known as diabetic nephropathy.
Over time, this damage reduces the kidney’s ability to filter waste, eventually leading to kidney failure. When conservative treatments no longer work, a kidney transplant is recommended to replace the damaged organ.
3. Kidney Failure Due to Hypertension (Hypertensive Nephrosclerosis)
Chronic high blood pressure can damage the small blood vessels in the kidneys, restricting blood flow to kidney tissue. Without proper control, this condition can lead to permanent kidney damage.
A kidney transplant becomes necessary when the kidneys can no longer recover their function due to long-standing hypertension.
4. Polycystic Kidney Disease (PKD)
Polycystic Kidney Disease (PKD) is a genetic disorder that causes numerous cysts to form inside the kidneys. Over time, these cysts enlarge and compress healthy kidney tissue, impairing its function and eventually leading to kidney failure.
At an advanced stage, kidney transplantation becomes the best option to restore lost filtration ability and replace permanently damaged kidneys.
5. Chronic Glomerulonephritis
Glomerulonephritis is inflammation of the kidney’s filtering units (glomeruli), which can occur due to infection, immune disorders, or systemic diseases. If inflammation persists without proper treatment, it may cause irreversible kidney damage.
When damage becomes widespread and medications are no longer effective, a kidney transplant is the only option to maintain bodily function.
6. Kidney Disease Caused by Autoimmune Disorders (Such as Lupus Nephritis)
Autoimmune diseases such as lupus can cause severe inflammation in the kidneys, known as lupus nephritis. If this inflammation leads to irreversible damage, the patient may develop complete kidney failure.
A kidney transplant is then performed to replace the failed organ, with careful immune system management to prevent organ rejection.
7. Kidney Damage Due to Medication or Severe Infection
Certain medications—such as long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) or specific antibiotics—can cause permanent kidney damage.
Additionally, recurrent severe kidney infections may also lead to irreversible kidney tissue damage. When medical therapy cannot restore kidney function, transplantation becomes the final option to regain normal kidney performance.
8. Complications from Kidney Disease Unresponsive to Dialysis
In some cases, patients with kidney failure who have undergone dialysis may not show significant improvement.
If serious complications arise—such as severe anemia, recurring electrolyte imbalances, or persistent weakness despite dialysis—doctors may recommend a kidney transplant as a more effective treatment option.
Kidney Transplant Hospital in Indonesia – RS Mandaya Royal Puri
RS Mandaya Royal Puri is one of the leading kidney transplant hospitals in Indonesia, equipped with advanced facilities and a multidisciplinary medical team to ensure the success of every transplant procedure.
Below are the supporting facilities for kidney transplantation at RS Mandaya Royal Puri:
1. Dedicated Kidney Transplant Operating Rooms (for Donor and Recipient)
RS Mandaya Royal Puri features specially designed operating rooms for kidney transplant procedures. The donor and recipient operating rooms are located side by side, allowing faster and safer organ transfer while maintaining optimal kidney quality.
Each room is equipped with high-standard sterilization systems, HEPA air filtration technology, and advanced monitoring devices to ensure patient safety and comfort during surgery.
The adjacent setup also minimizes the risk of cross-contamination while enabling the medical team to work efficiently and in coordination.
2. Laparoscopic Kidney Ultrasound
The Laparoscopic Kidney Ultrasound facility at RS Mandaya Royal Puri assists surgeons in performing kidney operations using minimally invasive techniques. This technology provides real-time and highly detailed visualization of kidney structures during surgery, helping doctors operate with precision, reduce bleeding risk, and accelerate post-surgery recovery.
This technology also enhances the safety and success rate of kidney transplant procedures.
3. Hemosphere Advanced Hemodynamic Monitor
RS Mandaya Royal Puri is also equipped with the Hemosphere Advanced Hemodynamic Monitor, a state-of-the-art system used to monitor the patient’s hemodynamic condition in real-time during kidney transplant surgery.
The device provides accurate data on blood pressure, circulation, and cardiac function, enabling anesthesiologists to make quick and precise decisions in response to any changes in the patient’s condition.
This monitoring system plays a vital role in maintaining patient stability both during surgery and throughout the recovery phase.
In addition to its advanced facilities, RS Mandaya Royal Puri is supported by a comprehensive multidisciplinary team, including specialists in urology, nephrology, anesthesiology, clinical pathology, and experienced nursing and rehabilitation staff.
For easier access to RS Mandaya Royal Puri, patients can use the Chat via WhatsApp, Book Appointment feature, or download the Care Dokter app via Google Play or the App Store to manage visits, check queue numbers, and obtain complete hospital information conveniently.
