Mandaya Royal Puri Hospital is the first hospital in Indonesia to offer HIPEC (Hyperthermic Intraperitoneal Chemotherapy) — a modern chemotherapy innovation proven effective for treating colorectal and ovarian cancers that have spread to the abdominal cavity (peritoneum).
Previously available only in major hospitals in Singapore and Malaysia, this advanced cancer therapy can now be accessed directly by patients in Indonesia through Mandaya Royal Puri Hospital.
Unlike conventional chemotherapy that requires multiple sessions, HIPEC is a single-session treatment that targets and destroys microscopic cancer cells inside the abdominal cavity directly — with fewer side effects.
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Understanding HIPEC and How It Works
HIPEC is a hyperthermic (heated) chemotherapy method designed to treat cancers that have spread to the peritoneum, the protective membrane surrounding vital organs such as the intestines, stomach, and liver.
The HIPEC procedure is performed after surgical removal of the primary tumor. Once the visible tumors are removed, a heated chemotherapy solution (40–50°C) is circulated directly into the abdominal cavity to destroy any remaining microscopic cancer cells.
The combination of heat and chemotherapy produces a synergistic effect that enhances treatment effectiveness and helps prevent cancer recurrence.
Stages of the HIPEC Procedure
The HIPEC procedure consists of two main stages, performed in a single surgical session:
1. Cytoreductive Surgery
The first stage focuses on removing as much visible tumor tissue as possible from the abdominal cavity. Under general anesthesia, the surgical team ensures all detectable cancer tissue is removed so the heated chemotherapy can work optimally.
2. Hyperthermic Chemotherapy (HIPEC)
Once the macroscopic tumors are removed, a heated chemotherapy solution is circulated through the abdominal cavity using a specialized perfusion machine.
The fluid is circulated for 1–2 hours to ensure it reaches all areas of the peritoneum, then drained and replaced with sterile fluid before carefully closing the incision.
Advantages of HIPEC Chemotherapy for Ovarian and Colorectal Cancer
HIPEC offers several significant benefits, making it one of the most effective treatment options for peritoneal cancer today:
- Targets areas unreachable by systemic chemotherapy
- Destroys microscopic cancer cells directly
- Uses high temperature (40–50°C) to increase drug effectiveness
- Requires only one procedure per treatment cycle
- Causes fewer side effects since the drug works locally
- Improves chances of recovery and prolongs survival in advanced cancer cases
HIPEC represents a new hope for patients with ovarian or colorectal cancer who previously had limited treatment options.
HIPEC Specialist Team for Ovarian and Colorectal Cancer at Mandaya Royal Puri Hospital
The HIPEC procedure at Mandaya Royal Puri Hospital is performed by an expert team of digestive surgery and gynecologic oncology specialists with extensive experience in managing peritoneal cancer and performing complex abdominal and gynecologic surgeries.
1. dr. Ocsyavina, Sp.B, Subsp.BD (K)
dr. Ocsyavina is a digestive surgery specialist experienced in treating various gastrointestinal diseases, including colorectal cancer, peritoneal tumors, and complex intestinal disorders. She is known for her precision, excellent communication, and strong commitment to patient safety and comfort. Every surgical procedure she performs is guided by a deep understanding of digestive anatomy and physiology.
Practice Schedule:
- Monday – Friday: 16.00 – 18.00 WIB
- Saturday: 10.00 – 12.00 WIB
2. dr. Emerson Budiarman Masli, Sp.B, Subsp.BD (K)
dr. Emerson Budiarman Masli is a digestive surgery specialist with strong expertise in treating digestive system conditions such as gallstones, hernias, appendicitis, liver cancer, and colorectal cancer. He is recognized for his careful and efficient surgical technique, minimizing postoperative complications.
Practice Schedule:
- Monday: 10.00 – 13.00 WIB
- Wednesday: 10.00 – 13.00 WIB
3. Prof. Dr. dr. Toar Jean Maurice Lalisang, Sp.B, Subsp.BD (K)
Prof. Toar Lalisang is a leading expert in digestive surgery in Indonesia. As a senior surgeon and educator, he has greatly contributed to advancing surgical knowledge and modern techniques, including the implementation of HIPEC procedures. His extensive experience covers major surgeries such as liver transplantation, pancreatic surgery, and colorectal tumor removal.
Practice Schedule:
- Tuesday: 15.30 – 17.30 WIB
- Thursday: 15.30 – 17.30 WIB
- Saturday: 11.00 – 13.00 WIB
4. dr. Ong Tjandra, M.Kes, Sp.OG (K), Subsp.Onk
dr. Ong Tjandra is an obstetrics and gynecology specialist with a subspecialty in oncology. He has extensive experience in managing ovarian, cervical, and uterine cancers, as well as benign tumors in the female reproductive system. He is known for his holistic approach, focusing not only on curing the cancer but also on improving patients’ post-therapy quality of life.
As part of the HIPEC team at Mandaya Royal Puri Hospital, dr. Ong plays a key role in evaluating advanced-stage ovarian cancer patients to determine the appropriateness and indications for the HIPEC procedure.
Practice Schedule:
- Monday: 10.00 – 17.00 WIB
- Thursday: 16.00 – 20.00 WIB
5. Dr. dr. Unedo Hence Markus Sihombing, Sp.OG, Subsp.Onk
Dr. Unedo Hence Markus Sihombing is a gynecologic oncology consultant specializing in cancers of the female reproductive system, including ovarian, endometrial, vulvar, and benign tumors such as fibroids and ovarian cysts. He is known for his compassionate approach and strong dedication to his patients.
In the HIPEC procedure, dr. Unedo plays an important role in advanced-stage ovarian cancer surgeries, combining oncologic surgery and intraperitoneal chemotherapy to achieve optimal treatment outcomes.
Practice Schedule:
- Tuesday: 16.00 – 20.00 WIB
- Thursday: 16.00 – 20.00 WIB
- Saturday: 13.00 – 16.00 WIB
If you wish to learn more or consult about the HIPEC chemotherapy procedure for colorectal or ovarian cancer that has spread to the abdominal cavity, visit Mandaya Royal Puri Hospital and meet the specialists listed above.
To make your visit easier, use the Chat via WhatsApp, Book Appointment feature, or the Care Dokter App, available on Google Play and App Store, to schedule visits, check queue numbers, and access complete hospital information conveniently.
